Vetri-SAMe (S-Adenosylmethionine / L-Glutathione)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Vetri-SAMe is a product to help dogs maintain optimal health and function of your pet's liver. SAMe is important for maintaining normal membrane function in liver cells. Glutathione (GSH) is a powerful antioxidant and the liver's primary line of defense.The GSH in this formula is enteric coated to ensure absorption in the small intestine. It also supports cognitive function. SAMe contributes to the balancing of the activity associated with brain neurotransmitters.It enhances the binding of neurotransmitters to receptor sites within the brain resulting in increased activity of Serotonin and Dopamine. The clinical evidence for the effectiveness of SAMe as a mood enhancing nutrient has been supported in nearly 100 published studies.


90mg for Small Dogs and Cats: up to 12 lbs. Give 1 tablet daily 225mg for Medium Dogs: 13-34lbs. Give 1 tablet daily 425mg for Larger dogs 35lbs and greater: 35 - 65 lbs: Give 1 tablet daily 66 - 120 lbs: Give 2 tablets daily 121 lbs and over: Give 3 tablets daily If giving more than 1 tablet per day, divide dose between AM and PM. Optimal absorption of SAMe occurs in the small intestine. For this reason, tablets are enteric coated to protect the ingredients from stomach acid. Do not crush or break tablets, as this damages the enteric coating and thereby inhibits absorption. For best results, give on an empty stomach one hour prior to feeding.


Active Ingredients Per Tablet: S-Adenosylmethionine (SAMe) 90 mg / L-Glutathione 10 mg Active Ingredients Per Tablet: S-Adenosylmethionine (SAMe) 225mg / L-Glutathione 20 mg Active Ingredients Per Tablet: S-Adenosylmethionine (SAMe) 425mg / L-Glutathione (Enteric Coated) 40mg Inactive Ingredients: crospovidone, magnesium stearate, microcrystalline cellulose, silicon dioxide, stearic acid Enteric Coating Ingredients: Include: glycerol triacetate, hydroxypropyl methylcellulose phthalate, red #40, titanium dioxide,yellow #10.


If your pet has any sort of reaction to SAMe, discontinue use immediately and consult your Veterinarian.

Side Effects

Vetri-SAMe (S-Adenosylmethionine / L-Glutathione) is a dietary supplement used to support liver health in pets. Some of the common side effects associated with its use include:

  1. Nausea: Some pets may experience mild to moderate nausea when they first start taking Vetri-SAMe. This usually subsides as the pet's body adjusts to the supplement.

  2. Diarrhea: Some pets may develop diarrhea after taking Vetri-SAMe, which is usually a temporary side effect.

  3. Increased thirst: Pets may drink more water after taking Vetri-SAMe, which is a normal reaction.

  4. Changes in appetite: Some pets may experience changes in appetite after taking Vetri-SAMe, such as increased hunger or loss of appetite.

  5. Stomach upset: Some pets may experience mild to moderate stomach upset, such as bloating or gas, after taking Vetri-SAMe.

  6. Allergic reactions: Rarely, pets may develop an allergic reaction to the ingredients in Vetri-SAMe. Signs of an allergic reaction include itching, hives, and difficulty breathing.

It's important to note that these side effects are rare and usually mild. If you notice any serious side effects or any symptoms that persist or worsen, contact your veterinarian right away.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that the use of the drug is safe, appropriate, or effective for your pet. See your veterinarian for medical advice and treatment for your pet if you have any concerns.