Frontline TopSpot (Fipronil)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Frontline Top Spot is a spot-on topical medication for dogs and cats that provides relief from fleas and American dog ticks, brown dog ticks, deer ticks, and lone star ticks. Top Spot can also be used to treat sarcastic mange in dogs and it also kills chewing lice. It is an FDA-approved medication and is known to be safe and effective. However, is only for use with dogs and cats that are 8 weeks of age or older. There are no weight restrictions related to the use Frontline Top Spot.

The active ingredient in Frontline Top Spot is fipronil (9.7%)


Frontline Top Spot should be administered once a month and in the following manner: 

  • Remove applicator from child-resistant package
  • Hold applicator upright and snap applicator tip away from face and body
  • Place applicator tip through animal's hair to the skin level between the shoulder blades
  • Squeeze applicator, applying entire contents in a single spot to the animal's skin
  • Avoid superficial application to the animal's hair
  • Only one applicator per treatment is needed


Fipronil 9.7% Inert Ingredients 90.3%


  • This product is for external use on dogs and cats 8 weeks or older
  • Persons applying this product may want to wear latex gloves
  • Consult a veterinarian before using on medicated animals, animals using this product with other pesticides, and debilitated, aged, pregnant, or nursing animals

Side Effects

Temporary irritation at site of product application

This information is for informational purposes only. It is not to be a substitute for the diagnosis, treatment, or professional advice of a veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition or the use of a particular medication.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for your pet. See your veterinarian for medical advice and treatment for your pet if you have any concerns.