Merck Frosst

Dispensed from a jurisdiction where this item is approved for sale.

This is a combination of two medicines used to treat high cholesterol. Ezetimibe works by reducing the amount of cholesterol that your body absorbs from your diet. Simvastatin is an HMG-CoA reductase inhibitor or "statin". It works by blocking an enzyme that is necessary for your body to make cholesterol. This medicine is used in combination with a low-cholesterol and low-fat diet. Keeping your cholesterol level under control may reduce your risk of heart problems and stroke. This medicine is not a cure for high cholesterol, but may help to control it. This medicine may also be used to treat other conditions as determined by your doctor.

Follow the directions for using this medicine provided by your doctor. This medicine may be taken on an empty stomach or with food. Take this medicine in the evening unless otherwise directed by your doctor. IF YOU ARE ALSO TAKING A BILE ACID SEQUESTRANT (such as cholestyramine, colestipol, or colesevelam), take this medicine at least 2 hours before or at least 4 hours after the bile acid sequestrant. DO NOT DRINK LARGE AMOUNTS OF GRAPEFRUIT JUICE (greater than 1 quart daily) or eat large amounts of grapefruit while taking this medicine. STORE THIS MEDICINE at room temperature between 68 and 77 degrees F (20 and 25 degrees C) in a tightly-closed container, away from heat and light. CONTINUE TAKING THIS MEDICINE even if you feel well. Most people with high cholesterol do not feel sick. Do not miss any doses. Taking this medicine at the same time each day will help you to remember. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

EZETIMIBE (eh-ZET-eh-mib) and SIMVASTATIN (SIM-va-stat-in)