Abbott Laboratories

This medicine is a thyroid hormone used to treat hypothyroidism in dogs by replacing thyroid hormone.

SYNTHROID comes in a tablet form and should be taken orally, exactly as prescribed by your physician. It is recommended to take a tablet once a day in the morning on an empty stomach, an hour before eating. Take the tablet with a full glass of water at the same time each day. SYNTHROID should be taken at least 4 hours apart from drugs that are known to interfere with its absorption.

For children and infants who have difficulty consuming tablets, crush the tablet and mix it with 1-2 teaspoons of water and give it immediately without food or formula.

It may take a few weeks before you notice the effects of the medication so do not stop taking the medication. It is advised to visit your physician, as your blood, liver and kidneys might need to be regularly tested to ensure the medication is working properly.

Before taking SYNTHROID, consult your physician to verify if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

SYNTHROID may not be recommended for certain situations and/or conditions, so share your medical history with your physician. Conditions such as increased thyroid hormones (thyrotoxicosis), decreased adrenal gland function, heart disease (such as coronary artery disease, irregular heartbeat), high blood pressure and diabetes may indicate this medication is not right for you. It is important to consult your physician about any health conditions such as:

• Diabetes mellitus
• Low levels of pituitary hormone
• Heart disease
• Angina
• Previous heart attack
• An unusual or abnormal reaction to SYNTHROID, other thyroid hormones, medications, foods, dyes or preservatives
• High blood pressure
• Dieting or on a weight loss program
• If you are pregnant, breast feeding or currently trying to become pregnant, make sure your doctor is aware of your maternal condition
• Advise your physician if you are planning to have surgery
• Tell your doctor about all prescription drugs, nonprescription drugs, and herbal products that you are using

As with any medication, there is the possibility of side effects while using SYNTHROID. If you experience any of the symptoms below and they continue to persist, talk to your physician immediately.

Common side effects of SYNTHROID may include:

• Tremors
• Weight loss
• Nausea and/or vomiting
• Increased appetite
• Headache
• Temporary hair loss
• Diarrhea
• Nervousness
• Irritability
• Stomach cramps
• Insomnia
• Sensitivity to heat
• Excessive sweating and/or fever
• Angina or irregular heartbeat
• Changes in menstrual cycle

• Chest pain
• Nervousness
• Fast/irregular heartbeat or pulse
• Excessive sweating or intolerance to heat
• Skin rash or hives
• Difficulty breathing, wheezing or shortness of breath
• Swelling of ankles, feet or legs

• Hives
• Difficulty breathing
• Swelling of your face, lips, tongue, or throat