Ergotamine and caffeine are used together to treat migraine headache. Ergotamine works by constricting blood vessel walls in the head, relieving dilation that causes the pain of migraine headaches. Caffeine helps the ergotamine to be absorbed into the bloodstream more effectively.
The tablets are most effective if taken at the first sign of a migraine headache. They are not effective for other types of headache. Relief is often obtained within one-half hour of taking the medication. Extra medication may be required if relief is not obtained within one-half hour (see maximum doses).
Cafergot (Ergotamine Tartrate-Caffeine)
