Sulfasalazine is a drug that is used primarily for treating ulcerative colitis. It is a prodrug, that is, it is not active in its ingested form. It is broken down by bacteria in the colon into 5-aminosalicylic acid (5-ASA), and sulfapyridine.
Directions:
Adult doses range from 1000 mg to 4000 mg daily. Sulfasalazine is administered 2 to 4 times daily depending on the disease for which it is used. Sulfasalazine should be taken with a full glass of water after meals or with food to minimize upset stomach. Patients with kidney diseases may need to use lower doses of sulfasalazine.